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Systems Biology

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Five Years of CViSB

CViSB is 5 years old as of this February! Looking back, we have made significant strides toward our goal of identifying the human and viral factors that determine the outcome of infection with Lassa, Ebola, and SARS-CoV-2 viruses.  CViSB’s multi-disciplinary team has collected clinical, immunological, and genomic data, combined multi-omics technologies  and applied high-throughput (HTP) experiments to our unique patient…
Michelle McGraw
March 24, 2023
News

NIAID’s Data Dissemination Working Group aims to open biomedical data to the world

Over the course of the COVID-19 pandemic, the research community has responded by sharing an unprecedented amount of data publicly, including millions of SARS-CoV-2 sequences, protein crystal structures, and in vitro assays which have allowed us to rapidly develop new diagnostics, treatments, and vaccines. Despite the widespread enthusiasm of the research community to share data publicly, however, disseminating and finding…
Michelle McGraw
March 6, 2023
Outbreak.info featurePress ReleasePublication

Two new papers demonstrate use of Outbreak.info as one-stop online source for COVID data

While COVID-19 may be transitioning from a “pandemic” to an “endemic” phase, it remains critically important to continue tracking the virus in real-time. In two new papers published in Nature Methods on Feb. 23, 2023, scientists at Scripps Research demonstrate the use of Outbreak.info as a standardized, searchable source of information on the COVID-19 virus and its many variants. Since the COVID-19 pandemic began,…
Kristian Andersen
February 23, 2023
MapPress Release

Launch of outbreak.info variant tracking

The Center for Viral Systems Biology (CViSB) at Scripps Research is tracking the prevalence of new variants of SARS-CoV-2—the virus behind the COVID-19 pandemic—and making this information publicly available to drive global research efforts. The daily situation reports appear on Outbreak.info, a website created by the same team in early 2020, shortly after the emergence of COVID-19. The new reports add to the website’s…
Kristian Andersen
February 17, 2021
Workshop

Systems Biology Workshop

We are pleased to announce the 2nd annual CViSB Systems Biology workshop February 24-26, 2020 in La Jolla, CA. This two-and-a-half day workshop will emphasize computational systems biology approaches to improved understanding of host response to viral infection, across a spectrum of methods and applications.  Among topics discussed in the presentations will be included: evolution of virus and host immune…
Michelle McGraw
December 17, 2019
abstractPublication

Zika surveillance study in Cell

A new CViSB study investigating smoldering 'hidden' outbreaks of Zika in the Americas was published on the cover of Cell. In this paper we used travel surveillance and genomic epidemiology to answer a simple question - "in 2017, was the epidemic over?". The short answer, is no - read the rest of the study for the long answer. The Zika…
Kristian Andersen
August 24, 2019
vhfcNews

CViSB Year in Review

The first year of CViSB has been a busy one. Receiving the NIH grant in February, 2018 prompted the onboarding of new scientists, research trips to West Africa, and a myriad of planning and coordination meetings. Samples from over 250 Lassa and Ebola patients were collected during trips to Kenema Government Hospital (KGH). The samples will be used to generate…
Kristian Andersen
May 21, 2019
brineyPublication

Can humans produce a quintillion antibodies?

An analysis by CViSB scientists at Scripps Research of billions of distinct antibody-producing immune cells sampled from human volunteers indicates that the human antibody “repertoire” is far larger than was once thought. The finding, reported online on January 21 in Nature, suggests that humans may be capable of producing as many as 10^18, or one quintillion, distinct antibodies. The study…
Kristian Andersen
January 24, 2019
workshopWorkshop

SysBio workshop

We are pleased to announce the first annual CViSB Systems Biology workshop February 20-22, 2019 in La Jolla, CA. The workshop will focus on viral systems biology and the application of phylogenetic methods on the study of viruses. In addition, participants will hear from expert science communicators about the importance of effectively conveying scientific findings to the public. Leading infectious…
Kristian Andersen
December 11, 2018