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Outbreak.info featurePress ReleasePublication

Two new papers demonstrate use of Outbreak.info as one-stop online source for COVID data

While COVID-19 may be transitioning from a “pandemic” to an “endemic” phase, it remains critically important to continue tracking the virus in real-time. In two new papers published in Nature Methods on Feb. 23, 2023, scientists at Scripps Research demonstrate the use of Outbreak.info as a standardized, searchable source of information on the COVID-19 virus and its many variants. Since the COVID-19 pandemic began,…
Kristian Andersen
February 23, 2023
Press ReleasePublication

Risk posed by Lassa virus in Africa may dramatically increase over the next 50 years

A CViSB study published in Nature Communications last week characterized the factors that support Lassa virus circulation in West Africa through analyzing environmental data associated with virus occurrence. The research team, led by postdoc Raphaëlle Klitting, utilized ecological niche modeling to pinpoint temperature, precipitation, and the presence of pastureland as key contributors to viral spread. Combining this analysis with projections…
Michelle McGraw
October 5, 2022
Press ReleasePublication

Early detection of SARS-CoV-2 variants in wastewater

The CViSB developed tool, Freyja, is helping scientists detect SARS-COV-2 variants circulating in a community before they appear in clinical tests. As described in the recent Nature publication describing the study,  wastewater sampling is a cheaper, faster, and more accurate way for public health officials and researchers to detect rising cases, and now, it can accurately determine the genetic mixture…
Michelle McGraw
July 11, 2022
Publication

CViSB study shows how Mardi Gras 2020 accelerated Louisiana’s first COVID-19 wave

A CViSB-led study published in Cell outlines how the New Orleans’ Mardi Gras festival of February 2020 appears to have driven one of the worst early outbreaks of COVID-19 in the United States. Investigators sequenced and analyzed the COVID-19-causing coronavirus, SARS-CoV-2, recovered from patients, as well as data on population movements, COVID-19 deaths, and other relevant sources of information for…
Michelle McGraw
July 30, 2021
Publication

Investigation of a rare Ebola relapse case in Central Africa

A CViSB collaboration recently published their findings on an important Ebola relapse case in the Democratic Republic of Congo. A 25-year-old man who had been vaccinated against Ebola in December of 2018 fell ill with the disease six months later. He received experimental treatments for Ebola and was released from the hospital on June 29th, 2019. Unfortunately, the illness returned…
Michelle McGraw
May 6, 2021
Publication

The emergence of SARS-CoV-2 in Europe and North America

Accurate understanding of the global spread of emerging viruses is critically important for public health responses and for anticipating and preventing future outbreaks. In a recent study published in Science, CViSB investigators and colleagues investigate when, where, and how the earliest sustained SARS-CoV-2 transmission networks became established in Europe and North America. The results suggest that rapid early interventions successfully…
Michelle McGraw
September 11, 2020
measles studyPublication

The history of measles

Many infectious diseases are thought to have emerged in humans after the Neolithic revolution. While it is broadly accepted that this also applies to measles, the exact date of emergence for this disease is controversial. In a recent study from CViSB investigators and colleagues, the genome of a 1912 measles virus was sequenced from a formalin-preserved lung, representing the oldest…
Kristian Andersen
January 11, 2020
abstractPublication

Zika surveillance study in Cell

A new CViSB study investigating smoldering 'hidden' outbreaks of Zika in the Americas was published on the cover of Cell. In this paper we used travel surveillance and genomic epidemiology to answer a simple question - "in 2017, was the epidemic over?". The short answer, is no - read the rest of the study for the long answer. The Zika…
Kristian Andersen
August 24, 2019
brineyPublication

Can humans produce a quintillion antibodies?

An analysis by CViSB scientists at Scripps Research of billions of distinct antibody-producing immune cells sampled from human volunteers indicates that the human antibody “repertoire” is far larger than was once thought. The finding, reported online on January 21 in Nature, suggests that humans may be capable of producing as many as 10^18, or one quintillion, distinct antibodies. The study…
Kristian Andersen
January 24, 2019
vic_abstract_cellPublication

Ebola study w. VIC consortium

In two papers published in Cell and Cell Host Microbe CViSB investigators, together with colleagues from our VIC sister consortium, describe in detail antibody responses to Ebola. By systematic analysis of a large set of more than 170 monoclonal antibodies to Ebola virus, the researchers show which immunological features play key roles in protection against the virus. The researchers aimed to…
Kristian Andersen
August 9, 2018
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