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measles studyPublication

The history of measles

Many infectious diseases are thought to have emerged in humans after the Neolithic revolution. While it is broadly accepted that this also applies to measles, the exact date of emergence for this disease is controversial. In a recent study from CViSB investigators and colleagues, the genome of a 1912 measles virus was sequenced from a formalin-preserved lung, representing the oldest…
Kristian Andersen
January 11, 2020
abstractPublication

Zika surveillance study in Cell

A new CViSB study investigating smoldering 'hidden' outbreaks of Zika in the Americas was published on the cover of Cell. In this paper we used travel surveillance and genomic epidemiology to answer a simple question - "in 2017, was the epidemic over?". The short answer, is no - read the rest of the study for the long answer. The Zika…
Kristian Andersen
August 24, 2019
brineyPublication

Can humans produce a quintillion antibodies?

An analysis by CViSB scientists at Scripps Research of billions of distinct antibody-producing immune cells sampled from human volunteers indicates that the human antibody “repertoire” is far larger than was once thought. The finding, reported online on January 21 in Nature, suggests that humans may be capable of producing as many as 10^18, or one quintillion, distinct antibodies. The study…
Kristian Andersen
January 24, 2019
vic_abstract_cellPublication

Ebola study w. VIC consortium

In two papers published in Cell and Cell Host Microbe CViSB investigators, together with colleagues from our VIC sister consortium, describe in detail antibody responses to Ebola. By systematic analysis of a large set of more than 170 monoclonal antibodies to Ebola virus, the researchers show which immunological features play key roles in protection against the virus. The researchers aimed to…
Kristian Andersen
August 9, 2018
lassa_rdtPublication

Rapid diagnosis of Lassa

A new study from VHFC researchers provide validation for a new rapid diagnostic test for Lassa fever. It is difficult to distinguish febrile illnesses that are common in West Africa from Lassa fever based solely on a patient’s clinical presentation. In this study, the field performance of recombinant antigen-based Lassa fever immunoassays was compared to that of quantitative polymerase chain…
Kristian Andersen
April 12, 2018