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Publication Archives | Center for Viral Systems Biology

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Can humans produce a quintillion antibodies?

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An analysis by CViSB scientists at Scripps Research of billions of distinct antibody-producing immune cells sampled from human volunteers indicates that the human antibody “repertoire” is far larger than was once thought. The finding, reported online on January 21 in Nature, suggests that humans may be capable of producing as many as 10^18, or one quintillion, distinct antibodies. The study…

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Ebola study w. VIC consortium

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In two papers published in Cell and Cell Host Microbe CViSB investigators, together with colleagues from our VIC sister consortium, describe in detail antibody responses to Ebola. By systematic analysis of a large set of more than 170 monoclonal antibodies to Ebola virus, the researchers show which immunological features play key roles in protection against the virus. The researchers aimed to…

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